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mcqs of
,
1 : Structure study helps in?
A
:
Build DNA
B
:
Make drugs
C
:
Grow cells
D
:
Block ATP
2 : Folding study helps in?
A
:
Immunity
B
:
Misfolding diseases
C
:
Growth
D
:
Blood flow
3 : Spike protein helps in?
A
:
Entry
B
:
Folding
C
:
DNA fix
D
:
Digestion
4 : Host-pathogen study shows?
A
:
Enzymes
B
:
Binding sites
C
:
Toxins
D
:
pH
5 : Domain study helps in?
A
:
Digestion
B
:
Folding
C
:
Drug design
D
:
Transport
6 : Drug blocks?
A
:
Hormone
B
:
RNA
C
:
ATP
D
:
Active site
7 : Spike protein study helped?
A
:
Diagnose
B
:
Block entry
C
:
Kill virus
D
:
Boost RNA
8 : RNase H in HIV-1 does what?
A
:
Joins DNA
B
:
Breaks RNA
C
:
Cuts proteins
D
:
Copied RNA
9 : What is an active site?
A
:
Protein tail
B
:
Folding point
C
:
Functional region
D
:
Energy source
10 : What does structural biology study?
A
:
DNA only
B
:
Lipids
C
:
Hormones
D
:
3D macromolecules
11 : What makes X-ray crystallography widely reliable?
A
:
It uses radiation
B
:
It's quick and non-invasive
C
:
It provides atomic-level detail
D
:
It's low in cost
12 : Which field benefits most from 3D protein structures?
A
:
Agriculture
B
:
Pharmaceuticals
C
:
Astronomy
D
:
Archaeology
13 : Proper folding ensures?
A
:
Storage
B
:
Shape
C
:
Function
D
:
Size
14 : Why is electron density important in molecular analysis?
A
:
It shows gene locations
B
:
It reveals molecular charge
C
:
It indicates atom positions
D
:
It measures atomic weight
15 : How did X-ray crystallography help during COVID-19?
A
:
It detected antibodies
B
:
It grew viral cultures
C
:
It revealed spike protein structure
D
:
It produced vaccines directly
16 : What is a major application of X-ray crystallography in health sciences?
A
:
Diagnosing viruses
B
:
Designing structure-based drugs
C
:
Counting red blood cells
D
:
Imaging organs
17 : Receptor-blocking drug effect?
A
:
Entry stops
B
:
DNA breaks
C
:
Protein dies
D
:
RNA slows
18 : What is the difference between diffraction pattern and density map?
A
:
One is chemical, the other is biological
B
:
Pattern is 3D; map is 2D
C
:
Pattern is raw data; map shows electron density
D
:
Pattern is colored; map is black & white
19 : Why must crystals be of high quality in crystallography?
A
:
To absorb more X-rays
B
:
To reduce pH fluctuations
C
:
To create clear diffraction patterns
D
:
To increase protein quantity
20 : How do we convert a diffraction pattern to a 3D structure?
A
:
Using X-ray images
B
:
Using computer algorithms
C
:
By sequencing DNA
D
:
Through centrifugation
21 : Misfolded proteins are?
A
:
Inactive
B
:
Useful
C
:
Soluble
D
:
Faster
22 : How does temperature affect protein crystallization?
A
:
It speeds up enzymatic reactions
B
:
It increases radiation exposure
C
:
It affects crystal formation quality
D
:
It destroys proteins
23 : Why is protein crystallization important in structure determination?
A
:
It helps in color development
B
:
It allows better absorption
C
:
It forms a repeating molecular pattern
D
:
It increases mutation rate
24 : What does a density map represent?
A
:
Cell organelles
B
:
Protein solubility
C
:
Electron distribution
D
:
Enzyme activity
25 : What is produced when X-rays hit a crystal?
A
:
Electromagnetic waves
B
:
Heat
C
:
Diffraction pattern
D
:
Chemical bond
26 : What is the role of protein crystals in X-ray crystallography?
A
:
To amplify the signal
B
:
To isolate DNA
C
:
To arrange molecules regularly
D
:
To stain proteins
27 : What does X-ray crystallography primarily study?
A
:
DNA replication
B
:
Protein structure
C
:
Gene expression
D
:
Cell signaling
28 : Who introduced the method of X-ray crystallography?
A
:
Watson and Crick
B
:
Linus Pauling
C
:
Bragg and Bragg
D
:
Rosalind Franklin
29 : Why is Ensembl useful in evolutionary biology?
A
:
For breeding programs
B
:
For creating vaccines
C
:
For comparing genomes of different species
D
:
For testing chemical toxicity
30 : Which algorithm would help a researcher align an unknown gene to known databases?
A
:
PCR
B
:
PDB
C
:
FASTA
D
:
SDS-PAGE
31 : A scientist wants to compare DNA of humans and chimpanzees. Which tool should be used?
A
:
PCR
B
:
BLAST
C
:
CRISPR
D
:
ELISA
32 : How can computational biology aid personalized medicine?
A
:
By designing artificial limbs
B
:
By identifying similar organisms
C
:
By analyzing individual genetic variations
D
:
By boosting cell growth
33 : In drug discovery, what role does computational biology play?
A
:
Manufacturing medicines
B
:
Predicting drug-protein interactions
C
:
Replacing clinical trials
D
:
Mixing drug chemicals
34 : What is a key use of FASTA?
A
:
DNA cloning
B
:
Sequencing errors
C
:
Sequence alignment and homology
D
:
Protein folding
35 : Which database supports visualizing gene models for species?
A
:
GenBank
B
:
FASTA
C
:
Ensembl
D
:
RCSB
36 : How does BLAST help in biological research?
A
:
It synthesizes proteins
B
:
It stores lab chemicals
C
:
It finds similarities between biological sequences
D
:
It copies RNA codes
37 : What is the purpose of the Protein Data Bank (PDB)?
A
:
To provide genome statistics
B
:
To store RNA libraries
C
:
To give 3D data of proteins and nucleic acids
D
:
To detect gene mutations
38 : How does computational biology support genomics?
A
:
By creating new genomes
B
:
By aligning protein shapes
C
:
By assembling and analyzing genome sequences
D
:
By growing DNA in labs
39 : Which database provides access to DNA sequences from various organisms?
A
:
Ensembl
B
:
GenBank
C
:
PDB
D
:
UniProt
40 : Which area uses computers to manage DNA, RNA, and protein sequences?
A
:
Embryology
B
:
Botany
C
:
Bioinformatics
D
:
Cytology
41 : What does proteomics focus on?
A
:
Lipid analysis
B
:
Gene sequencing
C
:
Protein structure and function
D
:
DNA fingerprinting
42 : Which field deals with the study of complete DNA within a cell?
A
:
Proteomics
B
:
Genomics
C
:
Bioinformatics
D
:
Transcriptomics
43 : What is the primary goal of computational biology?
A
:
To cure all genetic diseases
B
:
To store biological samples
C
:
To analyze biological data using computational tools
D
:
To synthesize artificial DNA
44 : What is a drug target?
A
:
Lipid chain
B
:
Protein site
C
:
Diseases
D
:
Enzyme buffer
45 : How does sequence homology help in disease treatment?
A
:
Identifying disease causes
B
:
Understanding disease mechanisms
C
:
Studying mutation
D
:
Comparing species
46 : How does sequence homology predict gene function?
A
:
By comparing sequences with known functions
B
:
By analyzing sequence length
C
:
By observing gene location
D
:
By studying mutations
47 : Why is structural homology useful in drug design?
A
:
Predict protein evolution
B
:
Design drugs for protein structures
C
:
Measure protein size
D
:
Study gene mutations
48 : What is structural homology?
A
:
Sequence similarity
B
:
Protein structure similarity
C
:
Gene duplication
D
:
Environmental similarity
49 : Why identify homologous genes in diseases?
A
:
Study environmental effects
B
:
Understand disease mechanisms
C
:
Eliminate diseases
D
:
Compare gene size
50 : Protein misfolding causes?
A
:
Healing
B
:
Energy gain
C
:
Diseases
D
:
Faster growth
51 : What does sequence homology show?
A
:
Species behavior
B
:
Evolutionary relationships
C
:
Environmental factors
D
:
Gene function
52 : What are paralogs?
A
:
Same species, gene duplication
B
:
Different species, same ancestor
C
:
Unrelated genes
D
:
Same function in species
53 : What is sequence homology?
A
:
Similarity in gene function
B
:
Similarity due to shared ancestry
C
:
Similarity based on environment
D
:
Genetic sequence difference
54 : What are orthologs?
A
:
Same species, gene duplication
B
:
Different species, same ancestor
C
:
Unrelated genes
D
:
Different function in species
55 : How does structural homology aid drug design?
A
:
Predict protein evolution
B
:
Design drugs targeting proteins
C
:
Measure molecular size
D
:
Observe protein behavior
56 : How does sequence homology show evolution?
A
:
Studying gene ancestry
B
:
Comparing species size
C
:
Environmental effects
D
:
Studying gene mutations
Biology 11th MCQs || Ilam Ghar
Chapter 7 : Structural and Computational Blology
Biology 11th
